Electron transport in DNA bases: An extension of the Geant4-DNA Monte Carlo toolkit

The purpose of this work is to extend the Geant4-DNA Monte Carlo toolkit include electron interactions with four DNA bases using a set cross sections recently implemented in Geant-DNA CPA100 models and available for liquid water. Electron interaction elastic scattering, ionisation, electronic excitation were calculated adenine, thymine, guanine cytosine. energy range extended relativistic electrons. Elastic scattering independent atom model amplitude derived from ELSEPA code. Relativistic Binary Encounter Bethe Vriens was used calculate ionisation sections. calculations based on water following same strategy These within option6 physics constructor its capability tracking electrons material addition Since nucleobases have different molecular structure than it important perform more accurate simulations especially because considered most radiosensitive cells. Differential integrated good agreement data literature all bases. Stopping power, inelastic mean free path new extension are done by other studies, high Some deviations shown at low range, which could be attributed models. Comparison shows obvious difference emphasizes need track codes better estimation radiation effects biological material.